Strontium nitrate suppresses chemically-induced sensory irritation in humans

Summary:
Strontium salts strongly reduces stinging, burning, and itching caused by irritating chemicals on the skin.

Abstract:
Skin care products are complex formulations that may cause sensory irritation symptoms, characterized by stinging, burning, and itching. Substances capable of counteracting sensory irritation are of great practical interest. Strontium salts have been demonstrated to inhibit sensory irritation […]

By |October 16th, 2015|Research|1 Comment

Strontium is a potent and selective inhibitor of sensory irritation

Summary:
Strontium salts strongly reduced skin irritation without side-effects, representing a new class of topical anti-inflammatories.

Abstract:
BACKGROUND: Irritant contact dermatitis occurs following topical exposure to many chemicals found in cosmetics, personal care products, drugs, and during occupational exposure. Signs and symptoms may include sensory irritation (sting, burn, and/or itch), erythema, edema, and vesiculation.OBJECTIVE: In […]

By |October 16th, 2015|Research|1 Comment

Innovative uses for zinc in dermatology

Abstract:
Severe zinc deficiency states, such as acrodermatitis enteropathica, are associated with a variety of skin manifestations, such as perioral, acral, and perineal dermatitis. These syndromes can be reversed with systemic zinc repletion. In addition to skin pathologies that are clearly zinc-dependent, many dermatologic conditions (eg, dandruff, acne, and diaper rash) have been associated and […]

By |October 14th, 2015|Research|0 Comments

Hidradenitis suppurativa and zinc: a new therapeutic approach. A pilot study

Abstract:
BACKGROUND: Hidradenitis suppurativa (Verneuil’s disease) is a chronic suppurative dermatosis involving apocrine glands with a severe impact on the quality of life, which is enhanced by the fact that the drugs usually prescribed are poorly effective.OBJECTIVE: We discuss a new therapeutic approach based on zinc salts.METHODS: We performed a pilot study on 22 patients, […]

By |October 14th, 2015|Research|0 Comments

Hidradenitis suppurativa: the role of deficient cutaneous innate immunity

Abstract:
OBJECTIVE: To evaluate the expression of innate immunity markers at the site of nodules caused by hidradenitis suppurativa (HS).DESIGN: Prospective analysis of 12 patients with HS.SETTING: Unité de Cancéro-Dermatologie, Nantes Hospital, Nantes; Service de Dermatologie, Poitiers Hospital, Poitiers; and Service de Dermatologie, Clinique de Courlancy, Reims, FrancePATIENTS: Twelve patients (Hurley stage I or II) […]

By |October 14th, 2015|Research|0 Comments

Zinc and the skin

Abstract:
Zinc is an essential trace element integrally involved in a wide range of metabolic processes required for tissue growth and repair as well as being necessary for maintaining host defences. Zinc deficiency can occur from lack of adequate dietary intake, decreased intestinal absorption, and increased losses in the gastrointestinal tract, urine, and sweat. The […]

By |October 14th, 2015|Research|0 Comments

Evidence supporting zinc as an important antioxidant for skin

Abstract:
Antioxidants play a critical role in keeping skin healthy. The antioxidant benefits of vitamin C and E are well known, but the importance of the trace mineral, zinc, has been overlooked. This article reviews the evidence supporting zinc’s antioxidant role in protecting against free radical-induced oxidative damage. Zinc protects against UV radiation, enhances wound […]

By |October 14th, 2015|Research|0 Comments

[Magnesium in skin allergy]

Abstract:
Magnesium is involved in many biological processes within the body. Magnesium deficiency causes many disorders, including impairment of immunity. This review summarizes present knowledge on the relationship between magnesium and skin allergy reactions. Special focus is on allergy types I and IV. At present the best knowledge is on allergy I. Magnesium deficiency in […]

By |October 12th, 2015|Research|0 Comments

[Skin symptoms in disorders of vitamin and mineral metabolism]

Abstract:
The daily vitamin intake of the Swiss population seems to be good. In certain situations or population groups a vitamin or mineral salt deficiency is still possible. It seems more useful to show the different changes of the skin, mucous membranes, hair or nails in the various vitamin or mineral salt deficiencies than to […]

By |October 12th, 2015|Research|0 Comments

Effects of magnesium deficiency–more than skin deep

Abstract:
Dead Sea and magnesium salt therapy are two of the oldest forms of treatment for skin disease and several other disorders, supported by a body of largely anecdotal evidence. In this paper we review possible pathways for penetration of magnesium ions through the epidermis to reach the circulation, in turn replenishing cellular magnesium levels. […]

By |October 12th, 2015|Research|0 Comments