Effects of magnesium and its mechanism on the incidence of reperfusion arrhythmias following severe ischemia in isolated rat hearts

Abstract:
Magnesium sulfate (Mg) has been widely used for the treatment of ventricular arrhythmias (VF) in patients with coronary artery disease. However, the mechanisms of prevention on the incidence of VF have not been defined. The aim of study was to investigate the role of Mg in the prevention of VF and the mechanism of […]

By |October 18th, 2015|Research|0 Comments

Magnesium supplementation in the prevention of arrhythmias in pediatric patients undergoing surgery for congenital heart defects

Abstract:
BACKGROUND: The efficacy of magnesium in the prevention of arrhythmias in pediatric patients after heart surgery remains unknown. Therefore we prospectively examined the effect of magnesium treatment on the incidence of postoperative arrhythmias in pediatric patients undergoing surgical repair of congenital heart defects.METHODS AND RESULTS: Twenty-eight pediatric patients undergoing heart surgery with cardiopulmonary bypass […]

By |October 18th, 2015|Research|0 Comments

Magnesium treatment of ventricular arrhythmias

Abstract:
The association between marked hypomagnesemia and arrhythmias, particularly those associated with digitalis intoxication, has long been recognized. More recently, acute intervention with magnesium in patients who are not hypomagnesemic has demonstrated arrhythmia suppression in 3 settings: digitalis intoxication, long QT-related arrhythmias and arrhythmias after acute myocardial infarction. Although the electrophysiologic effects of magnesium are […]

By |October 18th, 2015|Research|0 Comments

[Magnesium and arrhythmia]

Abstract:
Experimental and clinical studies have shown the antiarrhythmic activity of magnesium salts and the arrhythmogenic effect of hypomagnesemia. Both are observed mainly but not exclusively during treatment with digitalis. The Mg++ plays an essential role in transmembrane K+ exchange in that a deficit of magnesium leads to a loss of intracellular K+ which cannot […]

By |October 18th, 2015|Research|0 Comments

Effect of acute magnesium administration on the frequency of ventricular arrhythmia in patients with heart failure

Summary:
Giving magnesium to patients with heart failure reduces the frequency of their arrhythmias.

Abstract:
BACKGROUND: There is a high incidence of ventricular arrhythmia and sudden death in patients with heart failure. Unfortunately, currently available antiarrhythmic agents have only limited efficacy and may result in proarrhythmia and hemodynamic deterioration in these patients.METHODS AND RESULTS: We studied […]

By |October 18th, 2015|Research|1 Comment

Magnesium therapy of cardiac arrhythmias in critical-care medicine

Abstract:
A common complication of critically ill patients is cardiac tachyarrhythmia. The role played by magnesium is not well appreciated. Well-documented cases indicated that magnesium may be effective in controlling the rhythm when conventional methods fail. The following tachyarrhythmias respond favorably to magnesium: (1) intractable ventricular tachycardia and fibrillation, whether hypo- or normomagnesemic, (2) torsades […]

By |October 18th, 2015|Research|0 Comments

[Significance of magnesium in cardiac arrhythmias]

Abstract:
Magnesium is of great importance in cardiac arrhythmias. It increases the ventricular threshold for fibrillation. Sinus node refractoriness and conduction in the AV node are both prolonged. Main indications for intravenous application of magnesium are Torsade de pointes tachycardias, digitalis toxicity induced tachyarrhythmias and multifocal atrial tachycardias. Additionally, patients with ventricular arrhythmias due to […]

By |October 18th, 2015|Research|0 Comments

Intravenous magnesium for cardiac arrhythmias: jack of all trades

Abstract:
Intravenous magnesium has been used to prevent and treat many different types of cardiac arrhythmia. It has diverse electrophysiological actions on the conduction system of the heart; including prolonging sinus node recovery time, and reducing automaticity, atrioventricular nodal conduction, antegrade and retrograde conduction over an accessory pathway, and His-ventricular conduction. Intravenous magnesium can also […]

By |October 18th, 2015|Research|0 Comments

Risk of high dietary calcium for arterial calcification in older adults

Abstract:
Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or no beneficial impact on bone mineral density (BMD) and fracture rates […]

By |October 14th, 2015|Research|0 Comments